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Germ-cell specific inflammasome component NLRP14 negatively regulates cytosolic nucleic acid sensing to promote fertilization
Cytosolic sensing of nucleic acids initiates tightly regulated programs to limit infection. Oocyte fertilization represents a scenario when inappropriate responses to exogenous yet non-pathogen-derived nucleic acids would have negative consequences. We hypothesized that germ cells express negative r...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Immunity |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5674777/ https://ncbi.nlm.nih.gov/pubmed/28423339 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2017.03.020 |
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