Dying tumor cell-derived exosomal miR-194-5p potentiates survival and repopulation of tumor repopulating cells upon radiotherapy in pancreatic cancer

BACKGROUND: Tumor repopulation is a major cause of radiotherapy failure. Previous investigations highlighted that dying tumor cells played vital roles in tumor repopulation through promoting proliferation of the residual tumor repopulating cells (TRCs). However, TRCs also suffer DNA damage after rad...

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Bibliografiska uppgifter
I publikationen:Mol Cancer
Huvudupphovsmän: Jiang, Ming-jie, Chen, Yi-yun, Dai, Juan-juan, Gu, Dian-na, Mei, Zhu, Liu, Fu-rao, Huang, Qian, Tian, Ling
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2020
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104536/
https://ncbi.nlm.nih.gov/pubmed/32228703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-01178-6
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