Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program

The mitochondria of various tissues from mice, naked mole rats (NMRs), and bats possess two mechanistically similar systems to prevent the generation of mitochondrial reactive oxygen species (mROS): hexokinases I and II and creatine kinase bound to mitochondrial membranes. Both systems operate in a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Vyssokikh, Mikhail Y., Holtze, Susanne, Averina, Olga A., Lyamzaev, Konstantin G., Panteleeva, Alisa A., Marey, Maria V., Zinovkin, Roman A., Severin, Fedor F., Skulachev, Maxim V., Fasel, Nicolas, Hildebrandt, Thomas B., Skulachev, Vladimir P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104298/
https://ncbi.nlm.nih.gov/pubmed/32152094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916414117
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