Fluorescein Derivatives as Antibacterial Agents Acting via Membrane Depolarization

Appending a lipophylic alkyl chain by ester bond to fluorescein has been previously shown to convert this popular dye into an effective protonophoric uncoupler of oxidative phosphorylation in mitochondria, exhibiting neuro- and nephroprotective effects in murine models. In line with this finding, we...

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Udgivet i:Biomolecules
Main Authors: Nazarov, Pavel A., Kirsanov, Roman S., Denisov, Stepan S., Khailova, Ljudmila S., Karakozova, Marina V., Lyamzaev, Konstantin G., Korshunova, Galina A., Lukyanov, Konstantin A., Kotova, Elena A., Antonenko, Yuri N.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7072581/
https://ncbi.nlm.nih.gov/pubmed/32075319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10020309
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