Mild depolarization of the inner mitochondrial membrane is a crucial component of an anti-aging program

The mitochondria of various tissues from mice, naked mole rats (NMRs), and bats possess two mechanistically similar systems to prevent the generation of mitochondrial reactive oxygen species (mROS): hexokinases I and II and creatine kinase bound to mitochondrial membranes. Both systems operate in a...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Vyssokikh, Mikhail Y., Holtze, Susanne, Averina, Olga A., Lyamzaev, Konstantin G., Panteleeva, Alisa A., Marey, Maria V., Zinovkin, Roman A., Severin, Fedor F., Skulachev, Maxim V., Fasel, Nicolas, Hildebrandt, Thomas B., Skulachev, Vladimir P.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104298/
https://ncbi.nlm.nih.gov/pubmed/32152094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916414117
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