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Methionyl-tRNA Synthetase Regulates Lifespan in Drosophila

Methionyl-tRNA synthetase (MRS) is essential for translation. MRS mutants reduce global translation, which usually increases lifespan in various genetic models. However, we found that MRS inhibited Drosophila reduced lifespan despite of the reduced protein synthesis. Microarray analysis with MRS inh...

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Vydáno v:Mol Cells
Hlavní autoři: Suh, Yoon Seok, Yeom, Eunbyul, Nam, Jong-Woo, Min, Kyung-Jin, Lee, Jeongsoo, Yu, Kweon
Médium: Artigo
Jazyk:Inglês
Vydáno: Korean Society for Molecular and Cellular Biology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103878/
https://ncbi.nlm.nih.gov/pubmed/31940717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2019.0273
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