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Methionyl-tRNA Synthetase Regulates Lifespan in Drosophila

Methionyl-tRNA synthetase (MRS) is essential for translation. MRS mutants reduce global translation, which usually increases lifespan in various genetic models. However, we found that MRS inhibited Drosophila reduced lifespan despite of the reduced protein synthesis. Microarray analysis with MRS inh...

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Dettagli Bibliografici
Pubblicato in:Mol Cells
Autori principali: Suh, Yoon Seok, Yeom, Eunbyul, Nam, Jong-Woo, Min, Kyung-Jin, Lee, Jeongsoo, Yu, Kweon
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Society for Molecular and Cellular Biology 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103878/
https://ncbi.nlm.nih.gov/pubmed/31940717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2019.0273
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