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Methionyl-tRNA Synthetase Regulates Lifespan in Drosophila

Methionyl-tRNA synthetase (MRS) is essential for translation. MRS mutants reduce global translation, which usually increases lifespan in various genetic models. However, we found that MRS inhibited Drosophila reduced lifespan despite of the reduced protein synthesis. Microarray analysis with MRS inh...

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Publicat a:Mol Cells
Autors principals: Suh, Yoon Seok, Yeom, Eunbyul, Nam, Jong-Woo, Min, Kyung-Jin, Lee, Jeongsoo, Yu, Kweon
Format: Artigo
Idioma:Inglês
Publicat: Korean Society for Molecular and Cellular Biology 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103878/
https://ncbi.nlm.nih.gov/pubmed/31940717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2019.0273
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