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Methionyl-tRNA Synthetase Regulates Lifespan in Drosophila

Methionyl-tRNA synthetase (MRS) is essential for translation. MRS mutants reduce global translation, which usually increases lifespan in various genetic models. However, we found that MRS inhibited Drosophila reduced lifespan despite of the reduced protein synthesis. Microarray analysis with MRS inh...

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Detalhes bibliográficos
Publicado no:Mol Cells
Main Authors: Suh, Yoon Seok, Yeom, Eunbyul, Nam, Jong-Woo, Min, Kyung-Jin, Lee, Jeongsoo, Yu, Kweon
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Molecular and Cellular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103878/
https://ncbi.nlm.nih.gov/pubmed/31940717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2019.0273
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