Methionyl-tRNA Synthetase Regulates Lifespan in Drosophila

Methionyl-tRNA synthetase (MRS) is essential for translation. MRS mutants reduce global translation, which usually increases lifespan in various genetic models. However, we found that MRS inhibited Drosophila reduced lifespan despite of the reduced protein synthesis. Microarray analysis with MRS inh...

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Bibliographic Details
Published in:Mol Cells
Main Authors: Suh, Yoon Seok, Yeom, Eunbyul, Nam, Jong-Woo, Min, Kyung-Jin, Lee, Jeongsoo, Yu, Kweon
Format: Artigo
Language:Inglês
Published: Korean Society for Molecular and Cellular Biology 2020
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103878/
https://ncbi.nlm.nih.gov/pubmed/31940717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14348/molcells.2019.0273
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