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Oncolytic vaccinia virus delivering tethered IL-12 enhances antitumor effects with improved safety

Immune checkpoint blockade is arguably the most effective current cancer therapy approach; however, its efficacy is limited to patients with “hot” tumors, warranting an effective approach to transform “cold” tumors. Oncolytic viruses (especially properly armed ones) have positive effects on almost e...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Immunother Cancer
Main Authors: Ge, Yan, Wang, Haiyan, Ren, Jinghua, Liu, Weilin, Chen, Lingjuan, Chen, Hongqi, Ye, Junjie, Dai, Enyong, Ma, Congrong, Ju, Songguang, Guo, Zong Sheng, Liu, Zuqiang, Bartlett, David L
פורמט: Artigo
שפה:Inglês
יצא לאור: BMJ Publishing Group 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103801/
https://ncbi.nlm.nih.gov/pubmed/32209602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-000710
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