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Breast Cancer Screening Implications of Risk Modeling Among Female Relatives of ATM and CHEK2 Carriers

BACKGROUND: With increasing use of multi-gene panel tests, pathogenic and likely pathogenic (P/LP) variants are more frequently identified in the moderate-penetrance breast cancer genes ATM and CHEK2. Lifetime breast cancer risk among women with P/LP variants in these genes generally exceeds 20%, me...

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Podrobná bibliografie
Vydáno v:Cancer
Hlavní autoři: Weidner, Anne, Liggin, Mariel, Zuniga, Brenda, Tezak, Ann, Wiesner, Georgia, Pal, Tuya
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103510/
https://ncbi.nlm.nih.gov/pubmed/31967672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32715
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