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Clonal Hematopoiesis as a Model for Premalignant Changes During Aging
Over the course of the human lifespan, somatic DNA mutations accumulate in healthy tissues. This process has been most clearly described in blood and bone marrow, esophagus, colon and skin, but cumulative DNA damage likely affects all tissues of the body. While most acquired genetic variants have no...
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| 發表在: | Exp Hematol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7103509/ https://ncbi.nlm.nih.gov/pubmed/31838005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2019.12.001 |
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