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Clonal Hematopoiesis as a Model for Premalignant Changes During Aging

Over the course of the human lifespan, somatic DNA mutations accumulate in healthy tissues. This process has been most clearly described in blood and bone marrow, esophagus, colon and skin, but cumulative DNA damage likely affects all tissues of the body. While most acquired genetic variants have no...

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Bibliografiska uppgifter
I publikationen:Exp Hematol
Huvudupphovsmän: Steensma, David P., Ebert, Benjamin L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103509/
https://ncbi.nlm.nih.gov/pubmed/31838005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2019.12.001
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