Clonal Hematopoiesis at Crossroads of Aging, Cardiovascular Diseases, and Cancer: JACC Topic of the Week

A novel, common, and potent cardiovascular risk factor has recently emerged: clonal hematopoiesis of indeterminate potential (CHIP). CHIP arises from somatic mutations in hematopoietic stem cells that yield clonal progeny of mutant leukocytes in blood. Individuals with CHIP have a doubled risk of co...

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Vydáno v:J Am Coll Cardiol
Hlavní autoři: Libby, Peter, Sidlow, Robert, Lin, Amy E., Gupta, Dipti, Jones, Lee W., Moslehi, Javid, Zeiher, Andreas, Jaiswal, Siddhartha, Schulz, Christian, Blankstein, Ron, Bolton, Kelly L., Steensma, David, Levine, Ross L., Ebert, Benjamin L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681657/
https://ncbi.nlm.nih.gov/pubmed/31345432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.06.007
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