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Clonal Hematopoiesis of Indeterminate Potential Reshapes Biology of Age-Related CVD: JACC Topic of the Week

The incidence of cardiovascular diseases increases with age and is also correlated with increased inflammatory burden. Recently, human genetics provided a new paradigm linking aging, inflammation and atherosclerotic cardiovascular disease (ASCVD). Next-generation genetic sequencing of whole blood-de...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Coll Cardiol
Hauptverfasser: Khetarpal, Sumeet A., Qamar, Arman, Bick, Alexander G., Fuster, José J., Kathiresan, Sekar, Jaiswal, Siddhartha, Natarajan, Pradeep
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6662618/
https://ncbi.nlm.nih.gov/pubmed/31345433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2019.05.045
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