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Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes

Recent genetic analyses of large populations have revealed that somatic mutations in hematopoietic cells leading to clonal expansion are commonly acquired during human aging. Clonally restricted hematopoiesis is associated with an increased risk of subsequent diagnosis of myeloid or lymphoid neoplas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Steensma, David P., Bejar, Rafael, Jaiswal, Siddhartha, Lindsley, R. Coleman, Sekeres, Mikkael A., Hasserjian, Robert P., Ebert, Benjamin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4624443/
https://ncbi.nlm.nih.gov/pubmed/25931582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-03-631747
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