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Clonal hematopoiesis in human aging and disease

As people age, their tissues accumulate an increasing number of somatic mutations. While most of these mutations are of little or no functional consequence, a mutation may arise that confers a fitness advantage on a cell. When this process happens in the hematopoietic system, a substantial proportio...

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Publicado en:Science
Main Authors: Jaiswal, Siddhartha, Ebert, Benjamin L.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8050831/
https://ncbi.nlm.nih.gov/pubmed/31672865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan4673
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