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Structural basis of the zinc-induced cytoplasmic aggregation of the RNA-binding protein SFPQ
SFPQ is a ubiquitous nuclear RNA-binding protein implicated in many aspects of RNA biogenesis. Importantly, nuclear depletion and cytoplasmic accumulation of SFPQ has been linked to neuropathological conditions such as Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS). Here, we d...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7102971/ https://ncbi.nlm.nih.gov/pubmed/32034402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa076 |
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