Differences in inducibility of the latent HIV reservoir in perinatal and adult infection

The HIV latent reservoir in resting memory CD4(+) T cells precludes cure. Therapeutics to reactivate and eliminate this reservoir are in clinical trials in adults, but not yet in pediatric populations. We determined, ex vivo, the inducibility of the latent reservoir in perinatal infection as compare...

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Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Dhummakupt, Adit, Rubens, Jessica H., Anderson, Thuy, Powell, Laura, Nonyane, Bareng A.S., Siems, Lilly V., Collinson-Streng, Aleisha, Nilles, Tricia, Jones, R. Brad, Tepper, Vicki, Agwu, Allison, Persaud, Deborah
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101150/
https://ncbi.nlm.nih.gov/pubmed/31999647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134105
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