Clinical Validation of a Quantitative HIV-1 DNA Droplet Digital PCR assay: Applications for Detecting Occult HIV-1 Infection and Monitoring Cell-associated HIV-1 Dynamics across Different Subtypes in HIV-1 Prevention and Cure Trials

BACKGROUND. In HIV-1-exposed infants, nucleic acid testing (NAT) is required to diagnose infection since passively transferred maternal antibodies preclude antibody testing. The sensitivity of clinical NAT assays is lowered with infant antiretroviral prophylaxis and, with empiric very early antiretr...

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Publicat a:J Clin Virol
Autors principals: Powell, Laura, Dhummakupt, Adit, Siems, Lilly, Singh, Dolly, Le Duff, Yann, Uprety, Priyanka, Jennings, Cheryl, Szewczyk, Joseph, Chen, Ya, Nastouli, Eleni, Persaud, Deborah
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212401/
https://ncbi.nlm.nih.gov/pubmed/33930698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcv.2021.104822
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