Differences in inducibility of the latent HIV reservoir in perinatal and adult infection

The HIV latent reservoir in resting memory CD4(+) T cells precludes cure. Therapeutics to reactivate and eliminate this reservoir are in clinical trials in adults, but not yet in pediatric populations. We determined, ex vivo, the inducibility of the latent reservoir in perinatal infection as compare...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Dhummakupt, Adit, Rubens, Jessica H., Anderson, Thuy, Powell, Laura, Nonyane, Bareng A.S., Siems, Lilly V., Collinson-Streng, Aleisha, Nilles, Tricia, Jones, R. Brad, Tepper, Vicki, Agwu, Allison, Persaud, Deborah
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101150/
https://ncbi.nlm.nih.gov/pubmed/31999647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134105
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