Differences in inducibility of the latent HIV reservoir in perinatal and adult infection

The HIV latent reservoir in resting memory CD4(+) T cells precludes cure. Therapeutics to reactivate and eliminate this reservoir are in clinical trials in adults, but not yet in pediatric populations. We determined, ex vivo, the inducibility of the latent reservoir in perinatal infection as compare...

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Pubblicato in:JCI Insight
Autori principali: Dhummakupt, Adit, Rubens, Jessica H., Anderson, Thuy, Powell, Laura, Nonyane, Bareng A.S., Siems, Lilly V., Collinson-Streng, Aleisha, Nilles, Tricia, Jones, R. Brad, Tepper, Vicki, Agwu, Allison, Persaud, Deborah
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101150/
https://ncbi.nlm.nih.gov/pubmed/31999647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134105
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