Differences in inducibility of the latent HIV reservoir in perinatal and adult infection

The HIV latent reservoir in resting memory CD4(+) T cells precludes cure. Therapeutics to reactivate and eliminate this reservoir are in clinical trials in adults, but not yet in pediatric populations. We determined, ex vivo, the inducibility of the latent reservoir in perinatal infection as compare...

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發表在:JCI Insight
Main Authors: Dhummakupt, Adit, Rubens, Jessica H., Anderson, Thuy, Powell, Laura, Nonyane, Bareng A.S., Siems, Lilly V., Collinson-Streng, Aleisha, Nilles, Tricia, Jones, R. Brad, Tepper, Vicki, Agwu, Allison, Persaud, Deborah
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2020
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101150/
https://ncbi.nlm.nih.gov/pubmed/31999647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.134105
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