The microtubule targeting agents eribulin and paclitaxel activate similar signaling pathways and induce cell death predominantly in a caspase-independent manner

Microtubule-targeting agents (MTAs) are the most effective chemotherapeutics used in cancer therapy to date, but their clinical use is often hampered by the acquisition of resistance. Thereby, elucidation of the molecular signaling pathways activated by novel FDA-approved MTAs such as eribulin is im...

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Vydáno v:Cell Cycle
Hlavní autoři: Hüsemann, Lisa C., Reese, Alina, Radine, Claudia, Piekorz, Roland P., Budach, Wilfried, Sohn, Dennis, Jänicke, Reiner U.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100887/
https://ncbi.nlm.nih.gov/pubmed/31959066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2020.1716144
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