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Structure of the Neurotensin Receptor 1 in complex with β-arrestin 1
Arrestin proteins bind to active, phosphorylated G protein coupled receptors (GPCRs), thereby preventing G protein coupling, triggering receptor internalization, and affecting various downstream signaling pathways(1,2). While there exists a wealth of structural information delineating the interactio...
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| Publicat a: | Nature |
|---|---|
| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7100716/ https://ncbi.nlm.nih.gov/pubmed/31945771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-1953-1 |
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