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Cryo-EM structure of the activated GLP-1 receptor in complex with G protein
Glucagon-like peptide-1 (GLP-1) is a hormone with essential roles in regulating insulin secretion, carbohydrate metabolism and appetite. GLP-1 effects are mediated through binding to GLP-1R, a family B G protein-coupled receptor (GPCR) signaling primarily through the stimulatory G protein Gs. Family...
שמור ב:
| הוצא לאור ב: | Nature |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5587415/ https://ncbi.nlm.nih.gov/pubmed/28538729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22394 |
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