Structural Insights into Metabotropic Glutamate Receptor Activation

Metabotropic glutamate receptors are Family C G protein coupled receptors that form obligate dimers and possess extracellular ligand binding Venus flytrap (VFT) domains, which are linked via cysteine rich domains (CRDs) to their 7-transmembrane (7TM) domain. Spectroscopic studies show that signaling...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Koehl, Antoine, Hu, Hongli, Feng, Dan, Sun, Bingfa, Zhang, Yan, Robertson, Michael J, Chu, Matthew, Kobilka, Tong Sun, Pardon, Els, Steyaert, Jan, Tarrasch, Jeffrey, Dutta, Somnath, Fonseca, Rasmus, Weis, William I, Mathiesen, Jesper M, Skiniotis, Georgios, Kobilka, Brian K
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6709600/
https://ncbi.nlm.nih.gov/pubmed/30675062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-0881-4
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