Combined Effects of HLA-B*57/5801 Elite Suppressor CD8+ T Cells and NK Cells on HIV-1 Replication

Elite controllers or suppressors (ES) are HIV-1 infected individuals who maintain undetectable viral loads without anti-retroviral therapy. The HLA-B*57 allele is overrepresented in ES suggesting a role for HIV-specific CD8+ T cells in immune control. Natural killer (NK) cells also play a role in co...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: May, Megan E., Pohlmeyer, Christopher W., Kwaa, Abena K., Mankowski, Madeleine C., Bailey, Justin R., Blankson, Joel N.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cellular and Infection Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098910/
https://ncbi.nlm.nih.gov/pubmed/32266164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2020.00113
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