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HIV Type 1-Mediated Downregulation of HLA-B*57/B*5801 Proteins on Elite Suppressor CD4(+) T Cells

Elite controllers or suppressors (ES) are HIV-1-infected patients who maintain viral loads of <50 copies/ml without antiretroviral therapy. While HLA-B*57 and B*5801 alleles are overrepresented in ES, many HLA-B*57/B*5801 patients become chronic progressors (CP). We show here that HIV-1 infection...

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Main Authors: Sampah, Maame Efua S., Ceccato, Christina M., Blankson, Joel N.
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064525/
https://ncbi.nlm.nih.gov/pubmed/20919920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2010.0144
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