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CD8(+) T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants

BACKGROUND: Elite Controllers or Suppressors (ES) are HIV-1 positive individuals who maintain plasma viral loads below the limit of detection of standard clinical assays without antiretroviral therapy. Multiple lines of evidence suggest that the control of viral replication in these patients is due...

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Detalhes bibliográficos
Main Authors: Pohlmeyer, Christopher W, Buckheit, Robert W, Siliciano, Robert F, Blankson, Joel N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878989/
https://ncbi.nlm.nih.gov/pubmed/24330837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-152
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