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CD8(+) T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants

BACKGROUND: Elite Controllers or Suppressors (ES) are HIV-1 positive individuals who maintain plasma viral loads below the limit of detection of standard clinical assays without antiretroviral therapy. Multiple lines of evidence suggest that the control of viral replication in these patients is due...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pohlmeyer, Christopher W, Buckheit, Robert W, Siliciano, Robert F, Blankson, Joel N
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878989/
https://ncbi.nlm.nih.gov/pubmed/24330837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-152
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