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CD8(+) T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants

BACKGROUND: Elite Controllers or Suppressors (ES) are HIV-1 positive individuals who maintain plasma viral loads below the limit of detection of standard clinical assays without antiretroviral therapy. Multiple lines of evidence suggest that the control of viral replication in these patients is due...

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Autori principali: Pohlmeyer, Christopher W, Buckheit, Robert W, Siliciano, Robert F, Blankson, Joel N
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3878989/
https://ncbi.nlm.nih.gov/pubmed/24330837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-152
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