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Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets
The ubiquitin–proteasome system (UPS) and ubiquitin-like protein (UBL) conjugation pathways are integral to cellular protein homeostasis. The growing recognition of the fundamental importance of these pathways to normal cell function and in disease has prompted an in-depth search for small-molecule...
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| Publicat a: | Nat Rev Drug Discov |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7097807/ https://ncbi.nlm.nih.gov/pubmed/21151032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3321 |
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