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Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets

The ubiquitin–proteasome system (UPS) and ubiquitin-like protein (UBL) conjugation pathways are integral to cellular protein homeostasis. The growing recognition of the fundamental importance of these pathways to normal cell function and in disease has prompted an in-depth search for small-molecule...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Bedford, Lynn, Lowe, James, Dick, Lawrence R., Mayer, R. John, Brownell, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7097807/
https://ncbi.nlm.nih.gov/pubmed/21151032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3321
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