Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets

The ubiquitin–proteasome system (UPS) and ubiquitin-like protein (UBL) conjugation pathways are integral to cellular protein homeostasis. The growing recognition of the fundamental importance of these pathways to normal cell function and in disease has prompted an in-depth search for small-molecule...

Full description

Saved in:
Bibliographic Details
Published in:Nat Rev Drug Discov
Main Authors: Bedford, Lynn, Lowe, James, Dick, Lawrence R., Mayer, R. John, Brownell, James E.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7097807/
https://ncbi.nlm.nih.gov/pubmed/21151032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd3321
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items