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The Sts1 nuclear import adapter uses a non-canonical bipartite nuclear localization signal and is directly degraded by the proteasome

The proteasome is an essential regulator of protein homeostasis. In yeast and many mammalian cells, proteasomes strongly concentrate in the nucleus. Sts1 from the yeast Saccharomyces cerevisiae is an essential protein linked to proteasome nuclear localization. Here, we show that Sts1 contains a non-...

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Publicat a:J Cell Sci
Autors principals: Budenholzer, Lauren, Breckel, Carolyn, Hickey, Christopher M., Hochstrasser, Mark
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7097302/
https://ncbi.nlm.nih.gov/pubmed/32041904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.236158
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