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CD28-Dependent CTLA-4 Expression Fine-Tunes the Activation of Human Th17 Cells
Previous work has demonstrated that Th17 memory cells but not Th1 cells are resistant to CD28/CTLA-4 blockade with CTLA-4 Ig, leading us to investigate the individual roles of the CD28 and CTLA-4 cosignaling pathways on Th1 versus Th17 cells. We found that selective CD28 blockade with a domain antib...
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| Publicat a: | iScience |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7096747/ https://ncbi.nlm.nih.gov/pubmed/32203908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100912 |
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