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Braking Bad: Novel Mechanisms of CTLA-4 Inhibition of T Cell Responses
The coinhibitory receptor CTLA-4 is a master regulator of T cell responses and its function is critical in models of transplant tolerance. The CD28/CTLA-4 pathway is also an important therapeutic target, as the costimulation blocker belatacept was recently approved for use following renal transplant...
Enregistré dans:
| Publié dans: | Am J Transplant |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4364523/ https://ncbi.nlm.nih.gov/pubmed/25387592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12938 |
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