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Candida-Elicited Murine Th17 Cells Express High CTLA-4 Compared to Th1 Cells and Are Resistant to Costimulation Blockade

Effector and memory T cells may cross-react with allogeneic antigens to mediate graft rejection. While the costimulation properties of Th1 cells are well studied, relatively little is known about the costimulation requirements of microbe elicited Th17 cells. The costimulation blocker CTLA-4 Ig has b...

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Autori principali: Krummey, Scott M., Floyd, Tamara L., Liu, Danya, Wagener, Maylene E., Song, Mingqing, Ford, Mandy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071624/
https://ncbi.nlm.nih.gov/pubmed/24493820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301332
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