Interneuron Desynchronization Precedes Seizures in a Mouse Model of Dravet Syndrome

Recurrent seizures, which define epilepsy, are transient abnormalities in the electrical activity of the brain. The mechanistic basis of seizure initiation, and the contribution of defined neuronal subtypes to seizure pathophysiology, remains poorly understood. We performed in vivo two-photon calciu...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Tran, Conny H., Vaiana, Michael, Nakuci, Johan, Somarowthu, Ala, Goff, Kevin M., Goldstein, Nitsan, Murthy, Priya, Muldoon, Sarah F., Goldberg, Ethan M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2020
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096149/
https://ncbi.nlm.nih.gov/pubmed/32102923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2370-19.2020
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