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Interneuron Desynchronization Precedes Seizures in a Mouse Model of Dravet Syndrome

Recurrent seizures, which define epilepsy, are transient abnormalities in the electrical activity of the brain. The mechanistic basis of seizure initiation, and the contribution of defined neuronal subtypes to seizure pathophysiology, remains poorly understood. We performed in vivo two-photon calciu...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Tran, Conny H., Vaiana, Michael, Nakuci, Johan, Somarowthu, Ala, Goff, Kevin M., Goldstein, Nitsan, Murthy, Priya, Muldoon, Sarah F., Goldberg, Ethan M.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096149/
https://ncbi.nlm.nih.gov/pubmed/32102923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2370-19.2020
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