Interneuron Desynchronization Precedes Seizures in a Mouse Model of Dravet Syndrome

Recurrent seizures, which define epilepsy, are transient abnormalities in the electrical activity of the brain. The mechanistic basis of seizure initiation, and the contribution of defined neuronal subtypes to seizure pathophysiology, remains poorly understood. We performed in vivo two-photon calciu...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Tran, Conny H., Vaiana, Michael, Nakuci, Johan, Somarowthu, Ala, Goff, Kevin M., Goldstein, Nitsan, Murthy, Priya, Muldoon, Sarah F., Goldberg, Ethan M.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2020
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096149/
https://ncbi.nlm.nih.gov/pubmed/32102923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2370-19.2020
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