Interneuron Desynchronization Precedes Seizures in a Mouse Model of Dravet Syndrome

Recurrent seizures, which define epilepsy, are transient abnormalities in the electrical activity of the brain. The mechanistic basis of seizure initiation, and the contribution of defined neuronal subtypes to seizure pathophysiology, remains poorly understood. We performed in vivo two-photon calciu...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Tran, Conny H., Vaiana, Michael, Nakuci, Johan, Somarowthu, Ala, Goff, Kevin M., Goldstein, Nitsan, Murthy, Priya, Muldoon, Sarah F., Goldberg, Ethan M.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096149/
https://ncbi.nlm.nih.gov/pubmed/32102923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2370-19.2020
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