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Interneuron Desynchronization Precedes Seizures in a Mouse Model of Dravet Syndrome

Recurrent seizures, which define epilepsy, are transient abnormalities in the electrical activity of the brain. The mechanistic basis of seizure initiation, and the contribution of defined neuronal subtypes to seizure pathophysiology, remains poorly understood. We performed in vivo two-photon calciu...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Tran, Conny H., Vaiana, Michael, Nakuci, Johan, Somarowthu, Ala, Goff, Kevin M., Goldstein, Nitsan, Murthy, Priya, Muldoon, Sarah F., Goldberg, Ethan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096149/
https://ncbi.nlm.nih.gov/pubmed/32102923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2370-19.2020
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