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A Transient Developmental Window of Fast-Spiking Interneuron Dysfunction in a Mouse Model of Dravet Syndrome
Dravet syndrome is a severe, childhood-onset epilepsy largely due to heterozygous loss-of-function mutation of the gene SCN1A, which encodes the type 1 neuronal voltage-gated sodium (Na(+)) channel α subunit Nav1.1. Prior studies in mouse models of Dravet syndrome (Scn1a(+/−) mice) indicate that, in...
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| Pubblicato in: | J Neurosci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6125809/ https://ncbi.nlm.nih.gov/pubmed/30104343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0193-18.2018 |
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