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A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting

The triplet-based genetic code requires that translating ribosomes maintain the reading frame of a messenger RNA faithfully to ensure correct protein synthesis(1). However, in programmed -1 ribosomal frameshifting(2), a specific subversion of frame maintenance takes place, wherein the ribosome is fo...

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Dades bibliogràfiques
Publicat a:Nature
Autors principals: Namy, Olivier, Moran, Stephen J., Stuart, David I., Gilbert, Robert J. C., Brierley, Ian
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7094908/
https://ncbi.nlm.nih.gov/pubmed/16688178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04735
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