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A mechanical explanation of RNA pseudoknot function in programmed ribosomal frameshifting
The triplet-based genetic code requires that translating ribosomes maintain the reading frame of a messenger RNA faithfully to ensure correct protein synthesis(1). However, in programmed -1 ribosomal frameshifting(2), a specific subversion of frame maintenance takes place, wherein the ribosome is fo...
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| Gepubliceerd in: | Nature |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7094908/ https://ncbi.nlm.nih.gov/pubmed/16688178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature04735 |
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