Ribosomal Pausing at a Frameshifter RNA Pseudoknot Is Sensitive to Reading Phase but Shows Little Correlation with Frameshift Efficiency

Here we investigated ribosomal pausing at sites of programmed −1 ribosomal frameshifting, using translational elongation and ribosome heelprint assays. The site of pausing at the frameshift signal of infectious bronchitis virus (IBV) was determined and was consistent with an RNA pseudoknot-induced p...

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Bibliographic Details
Main Authors: Kontos, Harry, Napthine, Sawsan, Brierley, Ian
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC100026/
https://ncbi.nlm.nih.gov/pubmed/11713298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.24.8657-8670.2001
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