P2Y(12) Receptor Antagonist Clopidogrel Attenuates Lung Inflammation Triggered by Silica Particles

Silicosis is an occupational lung disease caused by inhalation of silica particles. It is characterized by intense lung inflammation, with progressive and irreversible fibrosis, leading to impaired lung function. Purinergic signaling modulates silica-induced lung inflammation and fibrosis through P2...

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Vydáno v:Front Pharmacol
Hlavní autoři: Santana, Patricia Teixeira, Luna-Gomes, Tatiana, Rangel-Ferreira, Marcos Vinicius, Tamura, Augusto Shuiti, Da Graça, Carolyne Lalucha Alves Lima, Machado, Mariana Nascimento, Zin, Walter Araujo, Takiya, Christina Maeda, Faffe, Debora Souza, Coutinho-Silva, Robson
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093325/
https://ncbi.nlm.nih.gov/pubmed/32256366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00301
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