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P2X7 Receptor Modulates Inflammatory and Functional Pulmonary Changes Induced by Silica
Silicosis is an occupational lung disease, characterized by irreversible and progressive fibrosis. Silica exposure leads to intense lung inflammation, reactive oxygen production, and extracellular ATP (eATP) release by macrophages. The P2X7 purinergic receptor is thought to be an important immunomod...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4195726/ https://ncbi.nlm.nih.gov/pubmed/25310682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110185 |
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