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The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis

BACKGROUND: Sepsis is associated with high mortality rates in intensive care units worldwide and represents a systemic inflammatory response to infection. P2X7 is an ionotropic purine receptor with known proinflammatory activity. Here, we investigated the role of the P2X7 receptor in sepsis induced...

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Detalhes bibliográficos
Publicado no:J Innate Immun
Main Authors: Santana, Patricia Texeira, Benjamim, Claudia Farias, Martinez, Camila Guerra, Kurtenbach, Eleonora, Takiya, Christina Maeda, Coutinho-Silva, Robson
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6738781/
https://ncbi.nlm.nih.gov/pubmed/25675986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000371388
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