P2Y(12) Receptor Antagonist Clopidogrel Attenuates Lung Inflammation Triggered by Silica Particles

Silicosis is an occupational lung disease caused by inhalation of silica particles. It is characterized by intense lung inflammation, with progressive and irreversible fibrosis, leading to impaired lung function. Purinergic signaling modulates silica-induced lung inflammation and fibrosis through P2...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Santana, Patricia Teixeira, Luna-Gomes, Tatiana, Rangel-Ferreira, Marcos Vinicius, Tamura, Augusto Shuiti, Da Graça, Carolyne Lalucha Alves Lima, Machado, Mariana Nascimento, Zin, Walter Araujo, Takiya, Christina Maeda, Faffe, Debora Souza, Coutinho-Silva, Robson
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7093325/
https://ncbi.nlm.nih.gov/pubmed/32256366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00301
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