Mutational and inhibitive analysis of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer-based assays

The 3C-like protease (3CL(pro)) of severe acute respiratory syndrome coronavirus (SARS-CoV) plays key roles in viral replication and is an attractive target for anti-SARS drug discovery. In this report, a fluorescence resonance energy transfer (FRET)-based method was developed to assess the proteoly...

Full description

Saved in:
Bibliographic Details
Published in:Biochem Biophys Res Commun
Main Authors: Kuang, Wan-Fen, Chow, Lu-Ping, Wu, Mei-Hua, Hwang, Lih-Hwa
Format: Artigo
Language:Inglês
Published: Elsevier Inc. 2005
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092943/
https://ncbi.nlm.nih.gov/pubmed/15883050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2005.04.072
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items