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Characterization and inhibition of norovirus proteases of genogroups I and II using a fluorescence resonance energy transfer assay
Noroviruses are the major cause of food- or water-borne gastroenteritis outbreaks in humans. The norovirus protease that cleaves a large viral polyprotein to nonstructural proteins is essential for virus replication and an attractive target for antiviral drug development. Noroviruses show high genet...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier Inc.
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259199/ https://ncbi.nlm.nih.gov/pubmed/22200497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.12.002 |
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