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Structural and Inhibitor Studies of Norovirus 3C-like Proteases
Noroviruses have a single-stranded, positive sense 7–8 kb RNA genome, which encodes a polyprotein precursor processed by a virus-encoded 3C-like cysteine protease (3CLpro) to generate mature non-structural proteins. Because processing of the polyprotein is essential for virus replication, norovirus...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3840063/ https://ncbi.nlm.nih.gov/pubmed/24055466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2013.09.008 |
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