A Codon-pair Deoptimized, Live-attenuated Vaccine Against Respiratory Syncytial Virus Is Immunogenic and Efficacious in Non-Human Primates

Despite a critical need for a respiratory syncytial virus (RSV) vaccine and decades of development efforts, a vaccine to protect infants, elderly, and other at-risk populations from RSV infection remains elusive. We have previously generated a new, live-attenuated vaccine candidate against RSV using...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Vaccine
Prif Awduron: Mueller, Steffen, Stauft, Charles B., Kalkeri, Raj, Koide, Fusataka, Kushnir, Anna, Tasker, Sybil, Coleman, J. Robert
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7092643/
https://ncbi.nlm.nih.gov/pubmed/32107060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.02.056
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